Hypertension in Children and Adolescents—More Questions Than Answers
In 2011, the National Heart, Lung, and Blood Institute Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents reiterated the recommendations in...
View ArticleUse of Diagnostic Tests in Adolescents With Essential Hypertension Use of...
ObjectiveTo describe the use of diagnostic tests in adolescents with essential hypertension.DesignLongitudinal analysis of administrative claims data.SettingMichigan Medicaid program during 2003 to...
View ArticleLong-term Follow-up of Patients After Childhood Urinary Tract Infection...
ObjectiveTo evaluate the long-term outcome of children with urinary tract infection (UTI).DesignFollow-up examination 6 to 17 years after childhood UTI.SettingSecondary to tertiary referral...
View ArticleDiminishing Importance of Screening and Treating Children for Vesicoureteral...
There are few issues in pediatrics that have generated as much controversy as the importance of identifying and treating vesicoureteral reflux (VUR) in children who have been diagnosed with a urinary...
View ArticleBlood Pressure Screening in Children and Adolescents Is the Glass Half Empty...
Hypertension is prevalent in adults and a potent risk factor for cardiovascular disease. Hypertension is present in 33.5% of adult men and women and a risk factor for myocardial infarction, stroke,...
View ArticleScreening for Elevated Blood Pressure in Children and Adolescents A Critical...
Although screening for elevated blood pressure (BP) in adults is beneficial, evidence of its beneficial effects in children is not clear. Elevated BP in children is associated with atherosclerosis...
View ArticlePicture of the Month—Quiz Case
A 12-year-old boy presented with painful hands and flexible wrists, which were first noticed at 3 years of age. He had no other medical or family history, but he had undergone several bilateral...
View ArticleLess Is More Combination Antibiotic Therapy for the Treatment of...
ImportanceDefinitive combination antibiotic therapy with a β-lactam and an aminoglycoside for the treatment of gram-negative bacteremia is commonly prescribed in pediatric patients; however, its...
View ArticleIdentification of Children and Adolescents at Risk for Renal Scarring After a...
ImportanceNo studies have systematically examined the accuracy of clinical, laboratory, and imaging variables in detecting renal scarring in children and adolescents with a first urinary tract...
View ArticleUrinary Tract Infections and Renal Damage Focusing on What Matters
In this issue of JAMA Pediatrics, Shaikh and colleagues report their analysis of risk factors for renal scarring in infants and young children following a urinary tract infection (UTI). The methods are...
View ArticlePreeclampsia, Placental Insufficiency, and Autism Spectrum Disorder or...
ImportanceIncreasing evidence suggests that autism spectrum disorder (ASD) and many forms of developmental delay (DD) originate during fetal development. Preeclampsia may trigger aberrant...
View ArticleAcute Kidney Injury Definition by Cystatin C Rise
This prospective cohort study of ICUs determines if defining clinical acute kidney injury (AKI) by cystatin C vs serum creatinine increases altered associations with biomarkers and outcomes in 287...
View ArticleTrends, Evaluation, and Management of Pediatric Nephrolithiasis
This review examines the increasing incidence, evaluation, and management of pediatric nephrolithiasis.
View ArticleProcalcitonin Use to Predict Bacterial Infection in Febrile Infants
This study of febrile infants reports that a procalcitonin assay has better diagnostic accuracy than C-reactive protein measurement for detecting invasive bacterial infection.
View ArticleTreatment Delay for Febrile Urinary Tract Infections
This study evaluates whether delay in the initiation of antimicrobial therapy for pediatric febrile urinary tract infections is associated with the occurrence and severity of renal scarring.
View ArticleAntibiotic Treatment for Febrile Urinary Tract Infection The Clock is Ticking
In this issue of JAMA Pediatrics, Shaikh et al report that early antibiotic treatment was associated with decreased risk of renal scarring in children with a first or second febrile urinary tract...
View ArticleKidney Outcomes 5 Years After Pediatric Cardiac Surgery
This cohort study assesses long-term kidney outcomes after pediatric cardiac surgery and explores whether perioperative acute kidney injury is associated with worse long-term kidney outcomes.
View ArticleAcute Kidney Injury in Children With Type 1 Diabetes
This study examines the incidence of and risk factors for acute kidney injury among children with type 1 diabetes who are hospitalized for diabetic ketoacidosis.
View ArticleAcute Kidney Injury in Children Admitted With Diabetic Ketoacidosis
Acute kidney injury (AKI), defined as an increase in serum creatinine levels and/or a decrease in urine output, is associated with worse short-term and long-term outcomes in children and adults....
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